• April 11th, 2016

Mustard Gas as a antineoplastic agent

Paper, Order, or Assignment Requirements

Essay: Researchers at Yale were the first to harness the reactivity of mustard gas by replacing the bivalent sulfur atom with a trivalent nitrogen atom. Discuss how the reactivity of the resulting nitrogen mustards can be controlled to give a perfectly-tuned antineoplastic agent. You may draw and annotate structures to help explain your answer. **One mechanism to depict how an archetypal nitrogen mustard reacts with DNA should be given.** The nucleophilic group of DNA that typically reacts with the mustards is the N7 position of guanine; for simplicity, refer to this as “DNA-NH2”.

Latest completed orders:

Completed Orders
# Title Academic Level Subject Area # of Pages Paper Urgency