• March 19th, 2016

Construct a pedigree for a family when given genotypes or phenotypes of the family members.

Paper, Order, or Assignment Requirements

TASK INSTRUCTIONS: Prepare a three-page report in which you draw and analyze the pedigree of the following family.

 

Subject: affected woman

Subject’s two brothers, unaffected

Subject’s father affected, mother unaffected

Subject’s paternal aunt and uncle, unaffected

Subject’s paternal grandfather affected, grandmother unaffected

 

In your 3-page report, present the following:

 

  1. Introduction Introduce the problem and list the data.

 

  1. Pedigree Chart Draw the pedigree according to the standard format.

 

  1. Identification Identify each individual in the pedigree with a number.

 

  1. Analysis In the Analysis section, make a section for possible modes of inheritance (autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive, Y-linked).

 

  1. Within each section assign putative genotypes to each individual in the pedigree (you may do this by labeling a diagram or listing the individuals). State whether the mode of inheritance is possible given the pattern in the pedigree. Make any other relevant comments.

 

  1. Conclusion State the conclusion of the analysis.

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